ORIGINAL ARTICLE

Uric acid level and the presence of metabolic syndrome: experiences from Vojvodina Region in Serbia

DS Popovic , E Stokic, D Tomic-Naglic, M Mitrovic, B Vukovic, D Benc, T Icin, B Kovacev-Zavisic

DS Popovic
Clinic for Endocrinology, Diabetes and Metabolic Disorders, Clinical Center of Vojvodina, Medical Faculty, University of Novi Sad, Serbia. Email: pitstop021@gmail.com

E Stokic
Clinic for Endocrinology, Diabetes and Metabolic Disorders, Clinical Center of Vojvodina, Medical Faculty, University of Novi Sad, Serbia

D Tomic-Naglic
Clinic for Endocrinology, Diabetes and Metabolic Disorders, Clinical Center of Vojvodina, Medical Faculty, University of Novi Sad, Serbia

M Mitrovic
Clinic for Endocrinology, Diabetes and Metabolic Disorders, Clinical Center of Vojvodina, Medical Faculty, University of Novi Sad, Serbia

B Vukovic
Emergency Center, Clinical Center of Vojvodina, Medical Faculty, University of Novi Sad, Serbia

D Benc
Clinic for Endocrinology, Diabetes and Metabolic Disorders, Clinical Center of Vojvodina, Medical Faculty, University of Novi Sad, Serbia

T Icin
Clinic for Endocrinology, Diabetes and Metabolic Disorders, Clinical Center of Vojvodina, Medical Faculty, University of Novi Sad, Serbia

B Kovacev-Zavisic
Clinic for Endocrinology, Diabetes and Metabolic Disorders, Clinical Center of Vojvodina, Medical Faculty, University of Novi Sad, Serbia
Online First: August 12, 2015 | Cite this Article
Popovic, D., Stokic, E., Tomic-Naglic, D., Mitrovic, M., Vukovic, B., Benc, D., Icin, T., Kovacev-Zavisic, B. 2015. Uric acid level and the presence of metabolic syndrome: experiences from Vojvodina Region in Serbia. Diabesity 1(3): 24-28. DOI:10.15562/diabesity.2015.16


Introduction: Uric acid level (UAL) might represent an indirect marker of metabolic syndrome (MS). Study investigates differences in UAL in the overall study group and in separate groups of normal weight, overweight and obese subjects, regarding the presence of MS. Materials and Methods: Cross sectional study included 1333 participants. Anthropometrical measurements and relevant blood analysis were performed. For diagnosis of MS we used NCEP ATP III criteria. Results: 50.64% of the participants have fulfilled criteria for MS diagnosis. In the overall study group, participants with MS were older (p<0.0001), more often male (p=0.0025), had higher BMI (p<0.0001) and UAL (p=0.0003). In the group of obese subjects, participants with MS were also older (p<0.0001), more often male (p<0.0001), had higher BMI (p=0.0084) and UAL (p=0.0014). In both cases, stepwise logistic regression showed independent association of all four parameters, which significantly differed in univariate analysis, with MS. In the group of normal weight subjects, participants with MS were more often male (p=0.0001), while in overweight subjects, participants with MS were older (p=0.0005). Conclusion: UAL is higher in subjects with MS in the overall study group and in the group of obese subjects, but not in groups of normal weight and overweight persons
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