Modulating Weight Loss and Regain through Exercise and Dietary Protein
Chaise A Murphy, Karsten Koehler
Efficacious weight loss which reduces risk of mortality requiresÂ both significant initial weight loss and prevention of weight regain.Â Performing either aerobic or resistance exercise and elevating proteinÂ intake during caloric restriction (CR) preservesâ€”and may increaseâ€”lean mass (LM), leading to targeted loss of fat mass. To maximizeÂ the LM retention stimulus achieved by consuming high-proteinÂ diets, gross and acute dosage, distribution and source of proteinÂ should all be optimized. Maintenance of LM during weight lossÂ may improve satiety during CR and aids in the prevention of weightÂ regain by blunting the post-CR hyperphagic response which causesÂ overcompensation of fat mass regain known as the fat overshootÂ phenomenon. Overall, the combination of exercise and high proteinÂ diet promotes efficacious weight loss through preservation of LM,Â which resists weight regain.